Download e-book for kindle: A Practical Guide to Rational Drug Design by Sun Hongmao

By Sun Hongmao

This booklet will not be an exhaustive survey protecting all elements of rational drug layout. in its place, it's going to offer serious information via real-world examples. proper case experiences can be awarded and analyzed to demonstrate the subsequent: how one can optimize a lead compound even if one has excessive or low degrees of structural details; find out how to derive hits from opponents’ lively compounds or from normal ligands of the pursuits; find out how to springboard from opponents’ SAR wisdom in lead optimization; the best way to layout a ligand to intrude with protein-protein interactions via appropriately reading the PPI interface; the right way to dodge IP blockage utilizing information mining; the best way to build and completely make the most of a knowledge-based molecular descriptor process; find out how to construct a competent QSAR version by way of targeting information caliber and correct number of molecular descriptors and statistical ways. A functional advisor to Rational Drug Design specializes in computational drug layout, with simply simple insurance of biology and chemistry concerns, akin to assay layout, goal validation and artificial routes.

  • Discusses various tactics appropriate to day-by-day drug layout
  • Readers can obtain the fabrics utilized in the ebook, together with constructions, scripts, uncooked information, protocols, and codes, making this e-book appropriate source for brief classes or workshops
  • Offers a different perspective on drug discovery learn a result of author’s cross-discipline schooling background 
  • Explores the author’s wealthy reviews in either pharmaceutical and educational settings

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A Practical Guide to Rational Drug Design by Sun Hongmao


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